In -Vivo Anti-Diabetic Activity of Hydro-Ethanolic Seed Extract of Syzygium Cumini (L.)

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Effects of ethanolic extract of Syzygium cumini (Linn) seed powder on pancreatic islets of alloxan diabetic rats.

The ethanolic extract of seeds of S. cumini increased body weight and decreased blood sugar level in alloxan diabetic albino rats. Level of significance for decrease in blood sugar after feeding alcoholic extract of S. cumini seeds in various doses was highly significant. The extract feeding showed definite improvement in the histopathology of islets. The most important finding is that the bloo...

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Pharmacological Screening of Ethanolic Extract of Syzygium Cumini Seed on Isolated Smooth Muscle Strip and Heart

Syzygium species are well known plants in the traditional system of Indian medicine with valuable medicinal properties like anti-hyperglycemic, anti-bacterial, hepato-protective, anti-diabetic, anti-inflammatory, chemopreventive, diuretic, etc. In our study, cumulative administration (936.55 μg/ml) of the ethanolic extract of Syzygium cumini seed relaxed (55 %) the rat uterus smooth muscle agai...

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Anti – Diabetic Activity of the Seed Kernel of Syzygium Cumini Linn

Syzygium cumini seed kernel (aqueous suspension) was screened for its antibiadetic activity at the dose levels of 1g., 2g., 4g and 6 g/kg body weight. 4g / kg dose level was found to exhibit maximum hypoglycaemic effect (42.64%) in rabbits, 3hr. after medication. Like Tolbutamide the drug may also be promoting endogenous release of insulin. An extra pancreatic site of action of the drug cannot ...

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Anti-inflammatory activity of Syzygium Cumini leaves

The Syzygium cumini (Myrtaceae) is a popular traditional medicinal plant in India. This study was intended to evaluate the antiinflammatory activity of ethyl acetate and methanol extracts of S.cumini leaves in carrageenan induced paw oedema in wistar rats at the dose level of 200 and 400 mg/kg administrated orally. Both the extracts exhibited significant anti-inflammatory activity, which suppor...

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Pharmacokinetics of Caffeic Acid from Methanol Seed Extract of Syzygium cumini L in Rats

Purpose: To describe caffeic acid-based pharmacokinetics of methanol extract of seed of Syzygium cumini L. in rats. Methods: A dose of the extract (500 mg, equivalent to 37.135 mg caffeic acid) was administered orally to 6 male Wister rats, weighing 200 ± 10 g. Blood samples (0.5 mL), collected from the tail vein at 0, 15, 30, 60, 120, 240 and 720 min, were processed and analyzed using high per...

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ژورنال

عنوان ژورنال: Biomedical and Pharmacology Journal

سال: 2021

ISSN: 0974-6242,2456-2610

DOI: 10.13005/bpj/2119